منابع مشابه
Choice of Ocular NSAIDS after Cataract Surgery
Context: The purpose of this study was to investigate the relative clinical efficacies of commonly used Ophthalmic NSAIDs following Small Incision Cataract Surgery with foldable PCIOL Implantation in an Indian setting, specially looking at the intra-operative pupil size, post -operative pain, discomfort, foreign body sensation and anterior chamber inflammatory cells ,flare grading and post-oper...
متن کاملTopical NSAIDs for musculoskeletal conditions. A review of the literature.
In recent years a growing number of topical nonsteroidal anti-inflammatory drugs (NSAIDs) have become available. This has been prompted in large part by the high incidence of serious gastrointestinal adverse events associated with the use of systemic NSAIDs, and the premise that minimisation of plasma concentrations of active drug may result in fewer systemic adverse effects. Evidence in humans...
متن کاملOcular delivery of macromolecules.
Biopharmaceuticals are making increasing impact on medicine, including treatment of indications in the eye. Macromolecular drugs are typically given by physician-administered invasive delivery methods, because non-invasive ocular delivery methods, such as eye drops, and systemic delivery, have low bioavailability and/or poor ocular targeting. There is a need to improve delivery of biopharmaceut...
متن کاملTopical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles.
PURPOSE Enhanced drug exposure to the ocular surface typically relies on inclusion of viscosity-enabling agents, whereas delivery to the back of the eye generally focuses on invasive means, such as intraocular injections. Using our novel mucus-penetrating particle (MPP) technology, which rapidly and uniformly coats and penetrates mucosal barriers, we evaluated if such drug formulations could in...
متن کاملTopical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides.
Purpose To evaluate the efficacy of anti-VEGF agents for treating choroidal neovascularization (CNV) when delivered topically using novel cell-penetrating peptides (CPPs) compared with delivery by intravitreal (ivit) injection. Methods CPP toxicity was investigated in cell cultures. Ivit concentrations of ranibizumab and bevacizumab after topical administration were measured using ELISA. The ...
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ژورنال
عنوان ژورنال: The AAPS Journal
سال: 2008
ISSN: 1550-7416
DOI: 10.1208/s12248-008-9024-9